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Table 4 Statistical comparison for the results obtained by the proposed spectrophotometric methods and the reported method for the analysis of PAR and IBUin pure powder form

From: Three smart spectrophotometric methods for resolution of severely overlapped binary mixture of Ibuprofen and Paracetamol in pharmaceutical dosage form

Value

RD

PAR

RD

IBU

MCR

CC

Reported methoda [5]

MCR

CC

Reported methoda [5]

Mean

99.95

99.91

99.64

100.25

100.14

100.18

99.97

99.63

SD

0.34

0.65

0.803

0.54

0.81

0.78

0.641

0.65

RSD%

0.340

0.650

0.806

0.538

0.808

0.778

0.641

0.652

n

5

5

5

5

5

5

5

5

Variance

0.115

0.422

0.645

0.291

0.656

0.608

0.411

0.422

Student’s t test(2.306)

1.036

0.1609

1.412

 

1.096

0.7081

0.834

 

F-value(6.388)

2.136

1.690

2.216

 

1.417

5.382

1.027

 
  1. The values in the parenthesis are the corresponding theoretical values of t and F at P = 0.05
  2. aSpectrophotometric method using derivative of the ratio spectra method
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BMC Chemistry

ISSN: 2661-801X

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