From: Synthesis and therapeutic potential of imidazole containing compounds
(a) | ||||||
---|---|---|---|---|---|---|
Compounds | Minimum inhibitory concentration in µg/mL | |||||
Antibacterial activity | ||||||
Gram positive bacteria | Gram negative bacteria | |||||
15a | 100 | 250 | 500 | 100 | 250 | 250 |
15b | 250 | 500 | 250 | 250 | 200 | 500 |
15c | 62.5 | 100 | 500 | 62.5 | 200 | 250 |
15d | 250 | 100 | 125 | 100 | 125 | 100 |
15e | 500 | 500 | 500 | 250 | 100 | 500 |
15f | 100 | 250 | 100 | 100 | 100 | 250 |
Ampicillin | 250 | 250 | 100 | 100 | 100 | 100 |
Chloramphenicol | 50 | 50 | 50 | 50 | 50 | 50 |
Ciprofloxacin | 50 | 100 | 50 | 25 | 25 | 25 |
(b) | ||
---|---|---|
Compounds | MIC | |
Antifungal activity | ||
C.albicans MTCC227 | T. rubrum MTCC296 | |
15a |  > 1000 | 1000 |
15b | 500 |  > 1000 |
15c | 1000 | 1000 |
15d | 1000 | 1000 |
15e | 1000 |  > 1000 |
15f | 500 | 1000 |
Nystatin | 100 | 500 |
Griseofulvin | 500 | 500 |