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Scheme 1 | BMC Chemistry

Scheme 1

From: Indole-carbohydrazide linked phenoxy-1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro α-glucosidase inhibition, and computational studies

Scheme 1

Synthetic routes to the new compounds 10a–o: a H2SO4, Methanol, Reflux, 12 h; b Hydrazine, Ethanol, RT, 6 h; c K2CO3, DMF, room temperature, 3 h; d DMF, RT, 30 min; e NaN3, NEt3, H2O/t-BuOH, 1 h; f CuSO4·5H2O, sodium ascorbate, RT, 24–48 h. g Acetic acid, Ethanol, RT, 6 h

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