Fig. 2From: Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemiaA The chemical structure of Gilteritinib, B The overall structure of the FLT3 kinase domain bound to Gilteritinib (PDB: 6JQR); the hinge region, juxtamembrane domain, and activation lobe are illustrated in black, C A detailed 3D representation of the interactions between FLT3 and Gilteritinib, D 2D structure of the FLT3 kinase domain bound to GilteritinibBack to article page