Fig. 3From: Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemiaA The chemical structure of Quizartinib, B The overall structure of the FLT3 kinase domain bound to Quizartinib (PDB: 4XUF); the hinge region, juxtamembrane domain, and activation lobe are illustrated in black; C A detailed 3D representation of the interactions between FLT3 and Quizartinib, D 2D structure of the FLT3 kinase domain bound to QuizartinibBack to article page