Fig. 7From: Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemiaSimple 2D diagram of the predicted binding modes of compound 16 into DFG-out FLT3 kinase homology (PDB: 4XUF); illustrating the two main hydrogen bonding interactions of compound 16 with Glu692 and Cys694, and one π-π stacking interaction with Phe830 in the DFG-out modelBack to article page