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Table 5 Result of PIO, ALO, GLM, and VLD determination in their dosage forms by the proposed MUPLC method and application of standard addition technique

From: Earth-friendly micellar UPLC technique for determination of four hypoglycemic drugs in different pharmaceutical dosage forms and spiked human plasma

Product

Found* % ± RSD

Standard addition

Taken

(µg/mL)

Added

Found**

(µg/mL)

Recovery%

prendaglim plus

PIO

101.23 ± 1.717

3

5

4.93

98.70

10

10.05

100.47

15

15.22

101.48

Mean

100.21

RSD%

1.407

ALO

100.57 ± 1.079

5

5

4.96

99.19

10

10.05

100.52

15

15.15

100.97

Mean

100.23

RSD%

0.922

Zanoglide

PIO

101.43 ± 1.195

15

5

5.07

101.34

10

10.21

102.05

15

15.25

101.67

Mean

101.69

RSD%

0.353

GLM

99.62 ± 1.736

2

5

5.01

100.17

10

9.87

98.71

15

14.86

99.04

Mean

99.31

RSD%

0.768

Prendaglim

ALO

100.88 ± 1.705

5

5

5.11

102.11

 

10

9.95

99.53

 

15

15.15

100.97

 

Mean

100.87

 

RSD%

1.279

 

Gliptus

VLD

101.33 ± 0.497

25

5

4.91

98.25

 

10

10.15

101.47

 

15

15.12

100.80

 

Mean

100.17

 

RSD%

1.692

 
  1. *Mean of five determinations
  2. **Mean of three determinations
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BMC Chemistry

ISSN: 2661-801X

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