Table 8 Assessment of the greenness of the proposed MUPLC method for the determination of PIO, ALO, GLM, and VLD utilizing the Eco-scale tool

Solvent

Propanol

2

2

4

SDS

0

0

0

Triethylamine

2

1

2

Phosphoric acid

2

1

2

Acetonitrile

2

1

2

Instrument

Energy (UPLC) [ 0.1 kWh per sample]

0

Occupational hazards (analytical process hermitization)

0

Waste

(1–10 mL, passivation)

5

Total Penalty points

Σ15

Analytical Eco-scale total scores ^{a b}

85