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Table 7 Penalty points calculated based on Eco Scale Score for the greenness evaluation of the present method

From: Mathematical processing of absorption as green smart spectrophotometric methods for concurrent assay of hepatitis C antiviral drugs, Sofosbuvir and Simeprevir: application to combined pharmaceutical dosage forms and evaluation of the method greenness

Item

Parameter

Word sign

PP score

Technique

Spectrophotometry

LSH

1

Reagent(s)

Non

 

0

Solvent

Ethanol (< 10 mL)

LSH

1

Heating

No heating

 

0

Temperature

Room temperature

 

0

Cooling

No cooling

 

0

Energy (kWh per sample)

 < 10 mL

 

0

Waste

1–10 mL

 

3

Occupational hazards

  

0

(TPPs)

  

5

Eco-scale total score

 = 100 − TPP

 

95

  1. MSH is an abbreviation for the more severe hazard, LSH for the Less severe hazard, and TPPs for the Total penalty points