A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors

Table 3 Accuracy and precision of the method for the determination of ALO⁺, SAX⁺ and VIL⁺ in the drug substances and pharmaceutical formulations

Drug		Conc. (mg/mL)	Found (mg/mL)	± SD	%Recovery (n = 3)	%Recovery (n = 9)	%RSD
ALO⁺		0.0462	0.0455	0.0005	98.50
	DS	0.0923	0.0909	0.0016	98.53
		0.1385	0.1346	0.0017	97.21
		0.0462	0.0455	0.0003	98.58
	Tablet	0.0923	0.0911	0.0015	98.72	98.31	0.60
		0.1385	0.1352	0.0016	97.63
SAX⁺
		0.0388	0.0380	0.0004	97.88
	DS	0.0776	0.0760	0.0008	98.02
		0.1164	0.1147	0.0023	98.56
		0.0388	0.0376	0.0005	97.04
	Tablet	0.0776	0.0758	0.0008	97.73	97.70	0.67
		0.1164	0.1144	0.0018	98.34
VIL⁺
		0.0303	0.0310	0.0005	102.16
	DS	0.0607	0.0607	0.0006	100.03
		0.0910	0.0924	0.0010	101.55
		0.0303	0.0305	0.0007	100.54
	Tablet	0.0607	0.0599	0.0005	98.71	99.61	0.92
		0.0910	0.0906	0.0010	99.58

ISSN: 2661-801X