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Table 2 In vitro cytotoxicity towards human MCT-7 (Breast), DU-145 (Prostate), and HCT-116 (Colon) cancer cell lines, expressed as mean growth inhibitory concentration 50% (IC50) values

From: Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents

Cell line target

IC50 (nM)

MCF-7

4.39

DU-145

1.06

HCT-116

0.34