From: Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents
Compound
(S) in kcal/mol
VEGFR-2
FGFR1
RET
15c
 − 12.94
 − 13.06
 − 13.04
Co-crystalized
ligand
 − 15.19
 − 17.00
 − 14.23