Compound | IC50 (μM) ± SD* | ||
---|---|---|---|
MCF-7 | MDA-MB-231 | MCF-10A | |
6f | 23.1 ± 0.94 | ≥ 50 | NT |
6a | 18.6 ± 0.69 | 19.8 ± 0.74 | NT |
6 h | 17.3 ± 0.31 | 21.3 ± 0.64 | NT |
7a | ≥ 50 | 26.5 ± 0.79 | NT |
7c | 12.4 ± 0.34 | ≥ 50 | NT |
8a | 31.2 ± 1.01 | 1.34 ± 0.13 | NT |
10a | ≥ 50 | 6.4 ± 0.18 | NT |
10f | 15.4 ± 0.28 | 8.6 ± 0.1 | NT |
10h | 16.4 ± 0.31 | 2.3 ± 0.1 | NT |
11a | 11.3 ± 0.29 | 7.2 ± 0.3 | NT |
11d | 2.1 ± 0.01 | 0.92 ± 0.01 | 39.4 ± 1.8 |
12c | 1.4 ± 0.05 | 1.89 ± 0.04 | 43.6 ± 1.9 |
12d | 1.9 ± 0.01 | 0.57 ± 0.09 | 41.6 ± 1.8 |
Erlotinib | 1.32 ± 0.04 | 1.02 ± 0.1 | 30.9 ± 1.8 |