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Table 10 Inhibition zone diameter of complexes in mm in vitro

From: Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation

Complexes

Antimicrobial activity

(Inhibition zone diameter (mm)

Mean ± S.E.M.

Bacterial species

Fungal strains

G + 

G − 

Bacillus subtilis

Staphylococcus aureus

Streptococcus faecalis

Escherichia coli

Neisseria gonorrhoeae

Pseudomonas aeruginosa

Aspergillus flavus

Candida albicans

Complex 1

16 ± 0.76

14 ± 1.04

15 ± 0.87

12 ± 0.43

13 ± 0.38

12 ± 0.07

0.0 ± 0.0

9 ± 0.19

 

A

A

A

A

A

A

A

A

Complex 2

11 ± 0.57

9 ± 0.28

11 ± 0.5

12 ± 0.58

12 ± 0.09

11 ± 0.31

11 ± 0.12

0.0 ± 0.0

 

B

B

A

A

A

A

B

B

Complex 3

13 ± 1.0

12 ± 0.86

18 ± 1.15

14 ± 0.14

13 ± 0.20

16 ± 0.52

9 ± 0.05

9 ± 0.34

 

B

A

B

A

A

B

C

A

Standard

        

Ampicillin antibacterial agent

26 ± 0.49

21 ± 0.69

27 ± 0.53

25 ± 0.23

28 ± 0.79

26 ± 0.26

–

–

 

C

C

C

B

B

C

  

Amphotericin B

–

–

–

–

–

–

17 ± 0.50

21 ± 0.01

Antifungal agent

      

D

C

  1. Different symbols indicate significant (p < 0.05) different means
  2. G, gram reaction