From: Hybridization of the effective pharmacophores for treatment of epilepsy: design, synthesis, in vivo anticonvulsant activity, and in silico studies of phenoxyphenyl-1,3,4-oxadiazole-thio-N-phenylacetamid hybrids
Entry
MW
Clog P
HBD
HBA
RBC
tPSA
Rule of five
< 500
< 5
< 10
–
Veber rule
< 140
Diazepam
284.74
2.97
0
2
1
32.67
Compound 8k
448.45
3.65
7
9
148.37
Compound 8L