Sustainable eco-friendly ratio-based spectrophotometric and HPTLC-densitometric methods for simultaneous analysis of co-formulated anti-migraine drugs with overlapped spectra

Table 2 Experimental results for the analysis of laboratory prepared mixtures using the developed methods

Laboratory prepared mixtures (µg/band or µg/mL)		HPTLC-densitometry		Spectrophotometric methods
		HPTLC-densitometry		RD		DRZC
		Recovery%^a
ASP	MET	ASP	MET	ASP	MET	ASP	MET
^b90	1	97.56	98.40	100.45	100.32	99.74	98.14
^b180	2	99.12	99.46	100.37	101.51	98.35	99.54
150	10	100.54	100.45	99.56	100.76	99.57	100.76
135	5	98.43	100.78	99.41	100.33	100.38	99.36
120	10	100.32	96.09	100.47	99.78	100.94	99.58
Mean recovery %		99.19	99.03	100.05	100.54	99.79	99.47
± SD		1.25	1.89	0.52	0.64	0.97	0.93

ISSN: 2661-801X