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Table 3 System suitability parameters of the developed HPTLC–densitometric method

From: Sustainable eco-friendly ratio-based spectrophotometric and HPTLC-densitometric methods for simultaneous analysis of co-formulated anti-migraine drugs with overlapped spectra

Parameters

ASP

MET

Reference values [34]

Rf

0.08 ± 0.03

0.7 ± 0.02

 

Tailing factor (T)

1.10

1.43

 ~ 1

Selectivity factor (α)

7.34

–

 > 1

Resolution (RS)

5.52

–

 > 1.5

  1. T = W0.05/2f, where W0.05 is the width of the peak at 5% height and f is the distance from peak maximum to the leading edge of peak
  2. α = k´2/k´1, where k´ is the capacity factor; k´ = (1–Rf)/Rf
  3. Rs = [2 (Rf2–Rf1)]/(W1 + W2), Where Rf is retardation factor and W is peak width