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Table 5 Statistical comparison for the results obtained by the proposed methods and the reported method for the analysis of ASP and MET in pure powder form

From: Sustainable eco-friendly ratio-based spectrophotometric and HPTLC-densitometric methods for simultaneous analysis of co-formulated anti-migraine drugs with overlapped spectra

Values

ASP

MET

aReported method [22]

HPTLC

RD

DRZC

HPTLC

RD

DRZC

Mean

99.16

100.74

99.55

101.43

100.41

99.81

99.76

SD

1.27

0.48

1.26

1.82

0.88

0.59

0.88

n

6

6

6

6

6

6

5

Variance

1.61

0.23

1.58

3.31

0.77

0.34

0.77

bStudent’s t-test

0.426 (2.306)

1.47 (2.26)

1.99 (2.26)

1.583 (2.306)

0.105 (2.145)

0.401 (2.145)

–

bF –value

1.613 (6.400)

3.497 (6.094)

2.943 (6.094)

1.158 (6.400)

1.486 (3.478)

1.486 (3.478)

–

  1. aThe factorized spectrum method for determination of ASP and MET
  2. bThe values between parenthesis are the theoretical values of t- and F-test at P = 0.05