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Table 6 Statistical analysis of the proposed methods to evaluate dorzolamide HCl in its ophthalmic dosage form using modified DRZ-PM/silica electrode

From: Electrochemically-selective electrode for quantification of dorzolamide in bulk drug substance and dosage form

Parameters

Proposed methods

Reported method (26)

Calibration curve

Potentiometric titration

Mean recovery

99.83 ± 0.38

100.1667 ± 0.34

99.82%

n

6

6

7

SD

0.38

0.34

0.205

Variance

0.146

0.118

0.042

Student t-test

0.058 (2.201)

2.15(2.201)

 

F-Test

3.47 (4.93)

2.8 (4.93)

 
  1. Confidence limit at 95%, SD standard deviation, n number of determinations, values between parenthesises are the critical values of Student t-test and F-value
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BMC Chemistry

ISSN: 2661-801X

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