Table 8 Antitumor activity of PTHAC and its metal complexes(1–3)
NO | Compound | Sample conc. (µg) | Viability % |
|---|---|---|---|
(1) | PTHAC (L) | 50 | 36.89 |
25 | 72.36 | ||
12.5 | 87.25 | ||
6.25 | 95.49 | ||
3.125 | 98.78 | ||
1.56 | 100 | ||
0 | 100.00 | ||
(2) | [Cu(L–H)Cl(EtOH)(H2O)].½EtOH.½ H2O | 50 | 40.73 |
25 | 62.89 | ||
12.5 | 73.94 | ||
6.25 | 87.32 | ||
3.125 | 94.56 | ||
1.56 | 98.14 | ||
0 | 100.00 | ||
(3) | [Co(L–H)Ac(EtOH)(H2O)].EtOH | 50 | 67.41 |
25 | 83.22 | ||
12.5 | 91.50 | ||
6.25 | 96.27 | ||
3.125 | 98.96 | ||
1.56 | 100 | ||
0 | 100.00 | ||
(4) | [Ni(L–H)EtOH] Cl | 50 | 74.93 |
25 | 88.62 | ||
12.5 | 95.28 | ||
6.25 | 98.71 | ||
3.125 | 100 | ||
1.56 | 100 | ||
0 | 100.00 |