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Table 3 The optimization results of the NADES-based UAE process

From: Green extraction of phenolics and flavonoids from black mulberry fruit using natural deep eutectic solvents: optimization and surface morphology

  

Factor

TPC

TFC

ABTS

OH

DPPH

 

Run

X1

X2

X3

X4

Forecast values

Experimental values

Forecast values

Experimental values

Forecast values

Experimental values

Forecast values

Experimental values

Forecast values

Experimental values

 

1

0

− 1

− 1

0

24.4

24.9 ± 0.4

14.7

14.6 ± 0.4

0.87

0.83 ± 0.10

7.4

7.2 ± 0.4

161

164 ± 7

 

2

0

0

− 1

1

32.5

32.7 ± 1.0

14.3

16.0 ± 1.0

1.02

1.00 ± 0.10

9.8

10.1 ± 0.2

175

176 ± 13

 

3

0

1

− 1

0

29.9

30.7 ± 1.5

17.2

16.9 ± 1.5

1.03

0.99 ± 0.09

8.3

8.6 ± 1.2

171

161 ± 9

 

4

0

0

− 1

− 1

24.2

25.8 ± 2.0

13.4

13.7 ± 2.0

0.76

0.97 ± 0.10

5.5

5.8 ± 0.7

165

167 ± 18

 

5

− 1

0

− 1

0

31.8

29.6 ± 1.1

15.2

15.3 ± 1.1

0.80

0.81 ± 0.08

7.8

7.6 ± 0.2

140

149 ± 8

 

6

1

0

− 1

0

31.4

30.7 ± 2.3

16.6

15.1 ± 2.3

1.07

0.99 ± 0.11

7.2

6.8 ± 2.3

194

189 ± 4

 

7

0

1

0

1

24.7

24.1 ± 0.9

13.4

12.2 ± 1.2

1.99

1.97 ± 0.05

10.1

9.9 ± 0.2

180

183 ± 11

 

8

1

0

0

− 1

23.3

23.2 ± 3.1

14.4

13.9 ± 0.4

1.50

1.64 ± 0.18

7.1

7.7 ± 0.2

194

195 ± 8

 

9

0

− 1

0

− 1

13.7

12.3 ± 0.1

10.8

11.6 ± 2.4

1.49

1.48 ± 0.25

7.0

7.0 ± 0.4

163

167 ± 6

 

10

1

1

0

0

29.5

28.9 ± 0.4

16.4

17.9 ± 1.4

1.78

1.75 ± 0.17

8.9

8.4 ± 0.2

186

198 ± 13

 

11

0

0

0

0

37.8

37.8 ± 0.7

25.5

25.5 ± 1.3

2.28

2.28 ± 0.05

4.9

4.9 ± 0.3

99

99 ± 6

 

12

− 1

0

0

− 1

24.2

24.6 ± 1.0

7.6

6.8 ± 0.6

1.74

1.53 ± 0.02

6.9

6.8 ± 0.2

145

145 ± 4

 

13

1

− 1

0

0

26.2

26.4 ± 0.6

13.8

14.8 ± 1.6

2.00

1.80 ± 0.16

8.8

8.6 ± 0.3

207

202 ± 18

 

14

0

0

0

0

37.8

37.8 ± 0.7

25.5

25.5 ± 1.3

2.28

2.28 ± 0.05

4.9

4.9 ± 0.3

99

99 ± 6

 

15

0

− 1

0

1

31.3

30.3 ± 4.0

11.0

10.2 ± 0.6

1.82

1.97 ± 0.08

10.0

10.0 ± 0.2

174

181 ± 16

 

16

0

0

0

0

37.8

37.8 ± 0.7

25.5

25.5 ± 1.3

2.28

2.28 ± 0.05

4.9

4.9 ± 0.3

99

99 ± 6

 

17

1

0

0

1

34.8

35.7 ± 1.1

11.7

11.5 ± 0.9

2.15

2.36 ± 0.44

10.3

10.8 ± 0.6

208

207 ± 9

 

18

− 1

1

0

0

26.7

27.1 ± 3.8

12.4

12.8 ± 0.6

2.09

2.31 ± 0.12

8.6

8.6 ± 0.1

161

160 ± 17

 

19

0

0

0

0

37.8

37.8 ± 0.7

25.5

25.5 ± 1.3

2.28

2.28 ± 0.05

4.9

4.9 ± 0.3

99

99 ± 6

 

20

0

0

0

0

37.8

37.8 ± 0.7

25.5

25.5 ± 1.3

2.28

2.28 ± 0.05

4.9

4.9 ± 0.3

99

99 ± 6

 

21

− 1

− 1

0

0

25.2

26.6 ± 2.9

12.1

12.0 ± 1.3

1.41

1.47 ± 0.04

7.8

8.1 ± 1.0

123

104 ± 13

 

22

− 1

0

0

1

30.0

31.3 ± 2.7

12.7

12.1 ± 0.5

1.64

1.51 ± 0.24

9.1

8.8 ± 0.1

149

148 ± 6

 

23

0

1

0

− 1

24.9

24.0 ± 1.4

11.3

11.7 ± 3.2

1.79

1.61 ± 0.11

7.8

7.5 ± 0.1

174

174 ± 12

 

24

− 1

0

1

0

24.7

23.5 ± 0.6

10.4

11.6 ± 0.1

1.03

1.09 ± 0.03

1.8

2.0 ± 0.6

100

111 ± 8

 

25

0

0

1

1

28.1

27.2 ± 0.6

11.2

12.2 ± 0.7

1.12

0.93 ± 0.02

3.5

3.1 ± 0.4

135

126 ± 4

 

26

0

1

1

0

22.0

22.8 ± 0.4

12.8

11.9 ± 0.3

1.19

1.26 ± 0.15

3.2

3.8 ± 0.3

130

126 ± 6

 

27

1

0

1

0

28.9

29.2 ± 0.6

14.8

14.5 ± 0.2

1.03

1.00 ± 0.02

3.8

3.8 ± 0.4

154

151 ± 20

 

28

0

0

1

− 1

19.0

19.5 ± 0.6

9.8

9.5 ± 0.3

0.84

0.88 ± 0.02

2.5

2.1 ± 0.5

127

120 ± 4

 

29

0

− 1

1

0

22.7

23.1 ± 1.2

12.4

11.6 ± 0.3

0.90

0.97 ± 0.11

3.2

3.3 ± 0.7

123

134 ± 22