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Table 2 Analytical parameters for determination of LIN and CEF mixture using the proposed CZE-DAD method

From: Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination

Parameter

LIN

CEF

Wavelength (nm)

250

285

Concentration range (μg/mL)

5–50

5–50

Intercept (a)

17.971

1.583

Saa

0.146

0.275

Slope (b)

1.098

1.381

Sbb

0.005

0.009

RSD% of the slope (Sb%)

0.455

0.652

Correlation coefficient (r)

0.9999

0.9999

Sy/xc

0.205

0.353

Fd

46,730

23,223

Significance F

2.04 × 10–11

1.11 × 10–8

LODe (μg/mL)

1.213

0.301

LOQf (μg/mL)

4.042

1.004

  1. aStandard deviation of the intercept
  2. bStandard deviation of the slope
  3. cStandard deviation of residuals
  4. dVariance ratio, equals the mean of squares due to regression divided by the mean of squares about regression (due to residuals)
  5. eLimit of detection
  6. fLimit of quantification