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Table 4 Determination of LIN and CEF in laboratory-prepared mixtures using the proposed CZE-DAD method

From: Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination

Nominal value (μg/ml)

Found ± SDa (μg/ml)

RSD (%) b

Er (%) c

 

LIN

  

Mixture 1 (LIN: CEF = 15:15)

15.15 ± 0.20

1.32

1.00

 

15.25 ± 0.20

1.31

1.67

Mixture 2 (LIN: CEF = 15:5)

29.58 ± 0.14

0.47

1.40

 

44.88 ± 0.11

0.25

0.27

 

CEF

  

Mixture 3 (LIN: CEF = 30:10)

15.06 ± 0.06

0.40

0.40

 

5.06 ± 0.06

1.19

1.20

Mixture 4 (LIN: CEF = 45:15)

10.01 ± 0.07

0.70

0.10

 

15.17 ± 0.25

1.65

1.13

  1. aMean ± standard deviation for five determinations
  2. b% Relative standard deviation
  3. c% Relative error
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BMC Chemistry

ISSN: 2661-801X

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