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Table 7 Penalty points of the proposed CZE-DAD method according to the Analytical Eco-scale in comparison with three previously reported methods

From: Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination

Evaluation Points

The proposed CZE methods

The reported 1st Spectrophotometric method [39]

The reported 2nd Spectrophotometric method [34]

The reported HPLC method [30]

1—Chemicals

    

Water

0

0

–

0

Borate buffer

1

–

–

–

Methanol

–

–

6

6

2—Energy

0

0

0

1

3—Occupational hazards

0

0

0

0

4—Waste

1

3

3

3

PPs

2

3

9

10

Eco-scale score

98

97

91

90