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Table 2 Toxicity bioresponses of the recently synthesized compounds towards the 2nd instar larvae of cotton leafworm, S. littoralis compared with methomyl insecticide, Lannate 90% SP after 7 days post treatment

From: Synthesis of inventive biphenyl and azabiphenyl derivatives as potential insecticidal agents against the cotton leafworm, Spodoptera littoralis

Tested compounds

LC50 (ppm) and confidence limits at 95%

LC90 (ppm) and confidence limits at 95%

Slope

Toxicity index % at LC50 value

Relative potency

Lannate

90% SP

25.396

57.860

3.584 ± 0.552

100

74.47

20.725

45.600

30.600

85.143

8d

113.860

1235.108

1.238 ± 0.207

22.31

16.61

75.479

653.341

165.348

3990.189

8a

146.265

1679.044

1.209 ± 0.205

17.36

12.93

98.758

836.464

217.972

6226.086

4b

216.624

2656.296

1.177 ± 0.206

11.72

8.73

147.368

1198.720

346.844

12500.646

8b

289.879

3381.256

1.201 ± 0.211

8.76

6.53

197.005

1467.575

492.252

17390.008

4c

400.239

4369.241

1.235 ± 0.220

6.35

4.73

267.559

1811.834

739.401

25266.588

4a

666.646

9419.460

1.114 ± 0.209

3.81

2.84

437.575

3615.027

1249.568

68880.669

4d

1048.448

12951.331

1.174 ± 0.208

2.42

1.81

710.313

5598.709

1758.127

67818.313

8c

1891.266

20255.647

1.245 ± 0.180

1.34

1.00

1320.721

9886.043

2980.333

68954.267

  1. Toxicity index is demarcated as the ratio of the utmost operative compound’s LC50 value to the other examined compound’s LC50 value multiplying by 100