Synthesis of inventive biphenyl and azabiphenyl derivatives as potential insecticidal agents against the cotton leafworm, Spodoptera littoralis

Table 3 The activities of Alk-P and Acid-p in Hemolymph of the 4th Instar Larvae of S. littoralis later 5 days of action with LC₅₀ of 8d, 8a, 4b, and 8b tested compounds

Tested compounds	Alkaline phosphatase (U/L)	% of control	Acid phosphatase (U/L)	% of control
8d	56.45 ± 0.28^e	− 41.99	18.37 ± 0.23^e	− 85.10
8a	62.47 ± 0.22^d	− 35.81	22.26 ± 0.27^d	− 81.94
4b	67.51 ± 0.23^c	− 30.63	26.08 ± 0.28^d	− 78.84
8b	71.22 ± 0.27^b	− 26.82	32.10 ± 0.44^b	− 73.96
Control	97.31 ± 0.22^a		123.23 ± 0.40^a

Whereby, means ± SE (standard error) of 3 replicates of 50 of 4th larvae each. Distinct letters designate significant variances between treatments as stated by Duncan’s test. LSD = 0.05 was 0.769 U/L for Alk-P and 1.048 U/L for Acid-p. % of control = (test−control)/control × 100

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