Synthesis of inventive biphenyl and azabiphenyl derivatives as potential insecticidal agents against the cotton leafworm, Spodoptera littoralis

Table 7 A-chE activity of A-chE in Hemolymph of the 4th Instar Larvae of S. littoralis later 5 days of treatment with LC₅₀ of 8d, 8a, 4b, and 8b tested compounds

Tested compounds	Acetyl cholinesterase activity (mU/mL)	% of control
8d	264.11 ± 0.76^e	− 65.50
8a	385.81 ± 0.86^d	− 49.61
4b	403.90 ± 1.06^c	− 47.24
8b	536.19 ± 1.30^b	− 29.96
Control	765.53 ± 1.63^a

Whereby, means ± SE (standard error) of 3 replicates of 50 of 4th larvae each. Distinct letters designate significant variances between treatments as stated by Duncan’s test. LSD = 0.05 was 3.663 mU/mL for acetyl cholinesterase. % of control = (test−control)/control × 100

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