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Fig. 4 | BMC Chemistry

Fig. 4

From: Discovery of novel 2,3,4,5-tetrahydrospiro[benzo[c]azepine-1,1’-cyclohexan]-5-ol derivatives as PARP-1 inhibitors

Fig. 4

Effects of compound 11b on the apoptosis in A549 cells. Cell apoptosis analysis was assessed in A549 cells during incubation with different concentrations for 48 h. Q1: Necrotic cell; Q2: Late apoptotic cell; Q3: Early apoptotic cell; Q4: Normal cell. Data were expressed as an average ≥ 3 determinations with standard deviation reported (**P < 0.01 and ***P < 0.001. Compound 11b-treated group VS control)

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BMC Chemistry

ISSN: 2661-801X

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