Fig. 5From: Discovery of novel 2,3,4,5-tetrahydrospiro[benzo[c]azepine-1,1’-cyclohexan]-5-ol derivatives as PARP-1 inhibitorsWestern blot analysis: A: Effects of compound 11b on PAR in A549 cells. B, C: Effect of compound 11b on Caspase 3 and Cleaved-Caspase 3 in A549 cells. Data were expressed as an average ≥ 3 determinations with standard deviation reported (*P < 0.05; **P < 0.01 and ***P < 0.001. Compound 11b -treated group VS control)Back to article page