Table 3 Binding score and interactions of compound 5 into the active cavity of β-tubulin protein
Binding score (kcal/mol) | Hydrophobic interactions | Hydrophilic interactions (Hydrogen bonding) | Distance (A) |
|---|---|---|---|
−11.89 | ALA354 | 3.23 | |
LEU255 | 2.36, 2.18 | ||
LEU248 | 3.84, 5.39 | ||
LEU255 | 3.59 | ||
ALA 316 | 4.27, 4.45 | ||
ALA354 | 3.5, 4.9 | ||
ILE318 | 4.62 | ||
LYS352 | 4.49 | ||
MET259 | 5.46 |