Table 4 Comparison of the solubilization powers of diversity cosolvents used for 5-ASA
Solvent mixtures | σ | ω |
|---|---|---|
Choline chloride/ethylene glycol + water | 1.42 | 1.42 |
Betaine/ethylene glycol + water [21] | 2.10 | 2.10 |
Betaine/propylene glycol + water [21] | 1.80 | 1.80 |
Choline chloride/propylene glycol + water [20] | 0.70 | 0.70 |
Ethylene glycol + water [4] | 1.15 | 1.15 |
1-propanol + water [12] | − 0.21 | 1.74 |
N-methyl-2-pyrrolidone + water [15] | 2.42 | 2.42 |
Propylene glycol + water [9] | 0.76 | 0.91 |
Ethanol + water [11] | − 0.21 | 1.05 |
2-propanol + water [13] | − 0.26 | 1.71 |
Acetonitrile + water [14] | − 0.90 | 1.80 |
Polyethylene glycol 400 + water [40] | 1.84 | 1.84 |