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Table 5 The CNIBS/R-K and modified Wilson model parameters and the corresponding MPD% for 5-ASA in ChCl/EG DES + water mixtures

From: Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 K

CNIBS/R-K model

 

S0

S1

S2

MPD%

293.2 K

− 0.395

NS a

NS

1.0

298.2 K

− 0.286

NS

NS

1.7

303.2 K

− 0.077

NS

NS

2.6

308.2 K

0.273

0.286

− 1.367

0.8

313.2 K

0.263

0.243

− 0.853

1.0

Overall MPD%

   

1.4

The modified Wilson model

 

λ23

λ32

MPD%

293.2 K

1.022

0.903

0.9

298.2 K

1.181

0.847

1.7

303.2 K

0.475

1.510

2.3

308.2 K

1.647

0.761

3.5

313.2 K

1.656

0.773

2.2

Overall MPD%

  

2.1

  1. a NS denotes to not statistically significant (p-value > 0.05)