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Table 6 The λh and van’t Hoff model parameters and the corresponding MPD% for the solubility of 5-ASA in ChCl/EG DES + water mixtures

From: Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 K

w2

λh model

van’t Hoff model

λ

h

MPD%

A

B

MPD%

0.0

0.503

68.616

0.7

3.927

− 2720.259

1.9

0.1

0.504

67.742

0.7

2.858

− 2358.173

1.2

0.2

0.504

82.819

2.1

3.451

− 2493.718

1.9

0.3

0.505

112.238

1.2

4.728

− 2824.897

1.7

0.4

0.506

0.0001

19.9

5.139

− 2884.878

1.8

0.5

0.508

0.0001

19.6

5.177

− 2843.381

2.8

0.6

0.509

176.462

0.9

4.677

− 2644.598

2.4

0.7

0.510

184.648

0.3

3.963

− 2383.805

1.3

0.8

0.512

183.989

1.1

2.939

− 2026.854

0.7

0.9

0.514

189.917

1.6

2.217

− 1752.760

1.1

1.0

0.517

0.0001

8.6

1.028

− 1334.946

1.0

Overall MPD%

5.1

  

1.6