Table 3 Analysis of LDC and MIC in their dosage form by the proposed TLC and RP-HPLC methods with the application of standard addition technique for RP-HPLC method
Drug | TLC-Densitometric | RP-HPLC | ||||
|---|---|---|---|---|---|---|
Claimed Concentration µg/ band | Recovery %a | Claimed concentration (µg mL−1) | Recovery%b | Added concentration (µg mL−1) | Recovery% | |
MIC | 2.50 | 98.80 ± 0.4 | 50.00 | 100.57 ± 1.301 | 15.00 | 98.20 |
30.00 | 100.13 | |||||
Mean ± SD | 45.00 | 101.84 | ||||
|  | Mean ± SD | 100.06 ± 1.821 | ||||
LDC | Claimed Concentration µg/ band | Recovery %a | Claimed concentration (µg mL−1) | Recovery%b | Added concentration (µg mL−1) | Recovery% |
0.66 | 99.49 ± 0.878 | 13.20 | 99.91 ± 1.334 | 8.00 | 99.50 | |
16.00 | 101.75 | |||||
Mean ± SD | 24.00 | 99.25 | ||||
|  | Mean ± SD | 100.17 ± 1.349 | ||||