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Table 5 Compounds 1(af), 2(ae), minimal inhibitory concentrations

From: Cu (II)-catalyzed: synthesis of imidazole derivatives and evaluating their larvicidal, antimicrobial activities with DFT and molecular docking studies

Comp. No

Minimum inhibitory concentration (MIC)/μg/Ml

Antibacterial activity

Antifungal activity

E. C

S. a

K. p

P. a

A. n

C. a

M. a

Cr. n

1a

 > 100

64

64

32

32

16

 > 100

16

1b

 > 100

 > 100

 > 100

64

16

0.5

64

 > 100

1c

32

 > 100

64

32

32

0.25

 > 100

64

1d

64

 > 100

 > 100

64

32

16

64

32

1e

 > 100

 > 100

32

 > 100

64

 > 100

 > 100

62

1f

 > 100

64

16

0.5

 > 100

 > 100

32

62

2a

 > 100

32

0.25

32

16

32

16

 > 100

2b

 > 100

16

64

 > 100

16

 > 100

16

62

2c

32

0.5

0.5

0.5

64

 > 100

32

62

2d

32

0.25

16

 > 100

 > 100

 > 100

32

16

2e

16

 > 100

16

16

32

16

32

 > 100

DMSO

Ciprofloxacin

0.5

0.5

32

0.25

Clotrimazole

32

0.5

08

32

  1. (–) nil active