Table 3 The docking scores and details of interactions between the compounds and PDGFRA obtained from the molecular docking calculations
From: Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives
Compounds | Docking score (kcal/mol) | Interactions with PDGFRA | Residue | Length |
|---|---|---|---|---|
7d | −7.584 | H-bond H-bond Pi-Pi stacking | Glu644 Asp836 Phe837 | 1.81 Å 2.38 Å 5.38 Å |
9 | −7.137 | Pi-cation H-bond H-bond | Lys627 Glu644 Asp836 | 3.84 Å 1.72 Å 2.16 Å |