Table 2 Anti-proliferative activity of compounds 4a‒4h against A549, HepG2, and RKO cell lines
From: Novel phenoxy-((phenylethynyl) selanyl) propan-2-ol derivatives as potential anticancer agents
Compound | IC50 (µm) | ||
|---|---|---|---|
A549 | HepG2 | RKO | |
4a | 97.91 ± 0.33 | 95.35 ± 0.89 | 97.74 ± 0.27 |
4b | 80.00 ± 0.18 | 75.84 ± 0.56 | 75.62 ± 0.20 |
4c | 59.40 ± 0.10 | 54.62 ± 0.83 | 40.31 ± 0.82 |
4d | 204.80 ± 0.93 | >4000 | 107.94 ± 0.40 |
4e | 88.54 ± 0.14 | >50,000 | 98.14 ± 0.35 |
4f | >20,000 | 393.00 ± 0.43 | 80.01 ± 0.29 |
4g | 117.80 ± 0.50 | >10,000 | 79.04 ± 0.33 |
4h | 53.44 ± 0.44 | 61.94 ± 0.20 | 57.99 ± 0.93 |