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Table 7 System suitability tests of the developed HPLC–DAD method for the simultaneous determination of ASP, ROS, ATV and CLP

From: An innovative combination of Box-Behnken design and ecofriendly approaches for the simultaneous determination of aspirin, clopidogrel, atorvastatin and rosuvastatin in their fixed-dose combination tablets

Parameter

ASP

ROS

ATV

CLP

Reference value

N

2974

58,620

23,660

67,625

The higher the value, the more efficient the column is

R

 

25.8

8.8

10.1

> 2

T

1.20

0.95

1.05

0.82

≤ 2

K′

1.02

3.45

4.55

5.90

1–10

α

 

12.95

1.32

1.30

≥ 1

  1. N number of theoretical plates, R resolution factor, T tailing factor, K′ capacity factor, α selectivity factor