From: An innovative combination of Box-Behnken design and ecofriendly approaches for the simultaneous determination of aspirin, clopidogrel, atorvastatin and rosuvastatin in their fixed-dose combination tablets
Parameter
ASP
ROS
ATV
CLP
Reference value
N
2974
58,620
23,660
67,625
The higher the value, the more efficient the column is
R
25.8
8.8
10.1
> 2
T
1.20
0.95
1.05
0.82
≤ 2
K′
1.02
3.45
4.55
5.90
1–10
α
12.95
1.32
1.30
≥ 1