Table 1 Accuracy intraday and interday and precision of quality control concentrations
QC concentration | Intraday | Interday | |||||
|---|---|---|---|---|---|---|---|
Added (ng/mL) | Found (ng/mL) | Found (%) ± RSD | Added (ng/mL) | Found (ng/mL) | Found (%) ± RSD | ||
NIRMA | LLOQ | 1000 | 1013 | 101.27 ± 4.86 | 1000 | 1005 | 100.51 ± 0.98 |
LQC | 3000 | 3129 | 104.30 ± 7.15 | 3000 | 3168 | 105.60 ± 5.47 | |
MQC | 10,000 | 9688 | 96.88 ± 10.92 | 10,000 | 10,250 | 102.50 ± 6.79 | |
HQC | 18,000 | 17,676 | 98.20 ± 1.93 | 18,000 | 18,762 | 104.23 ± 6.33 | |
Mean | 100.16 | 103.21 | |||||
% RSD | 6.22 | 4.891 | |||||
RITONA | LLOQ | 200 | 179 | 89.48 ± 13.05 | 200 | 182 | 91.02 ± 11.08 |
LQC | 6001 | 580 | 96.61 ± 11.25 | 6001 | 631 | 105.22 ± 7.09 | |
MQC | 6000 | 5778 | 96.30 ± 11.28 | 6000 | 5565 | 92.76 ± 4.87 | |
HQC | 18,000 | 17,972 | 99.85 ± 0.33 | 18,000 | 18,038 | 100.21 ± 1.64 | |
Mean | 95.56 | 97.30 | |||||
%RSD | 8.98 | 3.77 | |||||