Fig. 6From: Discovery of dual rho-associated protein kinase 1 (ROCK1)/apoptosis signal–regulating kinase 1 (ASK1) inhibitors as a novel approach for non-alcoholic steatohepatitis (NASH) treatmentThe selected pharmacophore model (Model 11) mapped onto the active compound 4 from ROCK1 test set (a) and compound 1 from ASK1 test set (b). Both compounds exhibited the lowest RMSD values amongst the other test set active compoundsBack to article page