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Table 14 The criteria used to filter molecules according to their pharmacokinetic properties

From: Discovery of dual rho-associated protein kinase 1 (ROCK1)/apoptosis signal–regulating kinase 1 (ASK1) inhibitors as a novel approach for non-alcoholic steatohepatitis (NASH) treatment

Criterion

Category

GIT absorption

High

BBB permeation

No

P-gp substrate

No

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BMC Chemistry

ISSN: 2661-801X

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