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Table 4 Penalty points (PPs) for proposed chemometric and reported HPLC methods

From: Development and validation of chemometric-assisted spectrophotometric models for efficient quantitation of a binary mixture of supportive treatments in COVID-19 in the presence of its toxic impurities: a comparative study for eco-friendly assessment

Parameters

Penalty points (PPs)

Proposed methods

Reported method [29]

Reagents

  

 Methanol

6.00

6.00

 Water

–

0.00

Instrument

  

 Energy (˃ 0.1kWh per sample)

0.00

1.00

 Occupational hazard

0.00

0.00

 Waste

1.00

5.00

Total PPs

Æ©7.00

Æ©12.00

93.00

88.00

Analytical Eco-scale score

Excellent green analysis

Excellent green analysis

  1. Analytical eco-scale score = 100 (the ideal score of green analytical method)
  2. Analytical eco-scale score > 75 (Excellent green analysis)
  3. Analytical eco-scale score 50–75 (the green analysis is acceptable)
  4. Analytical eco-scale score < 50 (the green analysis is inadequate