Table 5 Statistical analysis of the results obtained by the developed chemommetric methods and the reported HPLC methods for the determination of PAR and HYO in pharmaceutical preparation
Parameters | PAR | HYO | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Proposed methods | Reported methoda | Proposed methods | Reported methoda | |||||||
PLS | PCR | ANN | MCR-ALS | HPLC | PLS | PCR | ANN | MCR-ALS | HPLC | |
Meanb (%) | 100.93 | 100.68 | 100.41 | 100.90 | 101.85 | 100.89 | 100.72 | 100.55 | 100.77 | 101.52 |
SD | 0.86 | 0.75 | 0.72 | 0.77 | 0.48 | 0.85 | 0.65 | 0.88 | 0.83 | 0.52 |
Variance | 0.74 | 0.56 | 0.51 | 0.60 | 0.23 | 0.73 | 0.42 | 0.78 | 0.69 | 0.27 |
N | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 |
Student’s t-teste (2.23)c | 0.44 | 0.31 | 0.25 | 0.39 | – | 0.65 | 0.43 | 0.43 | 0.54 | – |
F-valuec (5.05)c | 3.15 | 2.41 | 2.20 | 2.55 | – | 2.65 | 1.54 | 2.83 | 2.50 | – |