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Table 10 Assay results for the determination of DRT, CAFF, and PAR in synthetic mixtures using derivative method

From: Smart green spectrophotometric assay of the ternary mixture of drotaverine, caffeine and paracetamol in their pharmaceutical dosage form

Mix. No

Ratio

Amount taken (µg/mL)

Amount found (µg/mL)

Percentage foundb

DRT

PAR

CAFF

DRT

PAR

CAFF

DRT

PAR

CAFF

1

1:1.5:10

2.00

3.00

20.00

2.019

3.006

19.887

100.95

100.20

99.44

2

1:1.5:10

3.00

4.50

30.00

2.964

4.472

30.23

98.8

99.38

100.77

3

1:1.5:10

4.00

6.00

40.00

4.017

6.001

39.884

100.43

100.00

99.71

Mean

 

100.06

99.86

99.97

 ± S.D

1.12

0.43

0.7

%RSD

1.12

0.43

0.7

%Error

0.65

0.25

0.41

ta

0.15

0.42

0.63

Fa

1.05

4.59

12.55

  1. aThe tabulated t and F values are 2.44, 6.94, respectively at P = 0.05 [81]
  2. bEach result was the average of three separate determinations