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Table 7 Assay results for determination of DRT, CAFF and PAR in pure forms in the derivative method

From: Smart green spectrophotometric assay of the ternary mixture of drotaverine, caffeine and paracetamol in their pharmaceutical dosage form

Proposed method

Comparison method (79)

Parameter

DRT

CAFF

PAR

DRT

CAFF

PAR

Amount taken µg/mL

Amount found µg/mL

% foundb

Amount taken µg/mL

Amount found µg/mL

%

foundb

Amount Taken µg/mL

Amount Found µg/mL

%

foundb

Amount taken µg/mL

% foundb

Amount Taken µg/mL

% foundb

Amount taken µg/mL

% foundb

 

2

2.013

100.65

1.5

1.494

99.60

5

5.085

101.7

6.00

100.65

6.00

98.97

15.00

98.93

4

3.940

98.50

3

3.040

101.33

10

10.127

101.27

8.00

98.60

8.00

98.29

20.00

101.90

6

5.988

99.80

6

6.051

100.85

15

15.152

101.01

10.00

100.52

10.00

101.17

30.00

100.93

8

7.921

99.01

9

8.919

99.10

20

20.168

100.84

 

10

9.966

99.66

12

11.871

98.93

30

30.189

100.63

14

14.166

101.19

15

15.125

100.83

40

40.704

101.76

Mean

  

99.73

  

100.11

  

100.51

 ± SD

0.93

1.02

1.08

ta

0.66 (2.36)

0.75 (2.36)

0.09 (2.36)

Fa

1.12 (5.76)

2.84 (5.76)

1.39 (5.76)

  1. aThe figures between parenthesis are the tabulated t and F values, respectively are at P = 0.05 [81]
  2. bEach result was the average of three separate determinations