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Table 8 Assay results for determination of DRT, CAFF and PAR in pure forms in the double divisor method:

From: Smart green spectrophotometric assay of the ternary mixture of drotaverine, caffeine and paracetamol in their pharmaceutical dosage form

Proposed method

Comparison method (79)

Parameters

DRT

CAFF

PAR

DRT

CAFF

PAR

Amount taken µg/mL

Amount found µg/mL

%

found b

Amount taken µg/mL

Amount found µg/mL

%

foundb

Amount taken µg/mL

Amount found µg/mL

%

foundb

Amount taken µg/mL

% foundb

Amount taken µg/mL

% foundb

Amount taken µg/mL

% foundb

 

2

1.995

99.75

1.5

1.506

100.40

2

1.973

98.65

6.00

100.65

6.00

98.97

15.00

98.93

4

3.942

98.55

3

3.025

100.83

5

4.94

98.80

8.00

98.60

8.00

98.29

20.00

101.90

8

7.949

99.36

6

6.001

100.00

10

9.974

99.74

10.00

100.52

10.00

101.17

30.00

100.93

10

10.009

100.09

9

8.912

99.02

20

20.087

100.44

 

14

14.210

101.72

12

11.886

99.05

30

30.28

100.93

20

19.85

99.30

15

15.051

100.34

40

39.78

99.45

Mean

  

99.79

  

99.94

  

99.66

 ± SD

1.07

0.75

0.89

ta

0.87 (2.36)

0.64 (2.36)

1.17 (2.36)

Fa

3.52 (19)

13.15 (19)

2.84 (5.76)

  1. aThe figures between parenthesis are the tabulated t and F values, respectively are at P = 0.05 [81]
  2. bEach result was the average of three separate determinations