BMC Chemistry

Table 9 Assay results for determination of DRT, CAFF and PAR in pure forms in the mean centering method

From: Smart green spectrophotometric assay of the ternary mixture of drotaverine, caffeine and paracetamol in their pharmaceutical dosage form

Proposed method										Comparison method (79)
Parameters	DRT			CAFF			PAR			DRT		CAFF		PAR
Parameters	Amount taken µg/mL	Amount found µg/mL	% found ^b	Amount taken µg/mL	Amount found µg/mL	% found^b	Amount taken µg/mL	Amount found µg/mL	% found^b	Amount taken µg/mL	% found^b	Amount taken µg/mL	% found^b	Amount taken µg/mL	% found^b
	2	2.026	101.3	1.5	1.515	101.00	2	1.996	99.80	6.00	100.65	6.00	98.97	15.00	98.93
	4	3.957	98.93	3	3.052	101.73	5	4.989	99.78	8.00	98.60	8.00	98.29	20.00	101.90
	6	5.989	9982	4.5	4.480	99.56	10	10.104	101.04	10.00	100.52	10.00	101.17	30.00	100.93
	8	7.918	98.98	6	6.017	100.28	20	19.696	98.48
	10	10.126	101.26	9	8.866	98.51	30	30.327	101.09
	20	19.981	99.91	15	15.068	100.45	40	98.867	99.67
Mean			100.03			100.25			99.97
± SD	1.05			1.12			0.98
t^a	0.14 (2.44)			0.88 (2.44)			0.75 (2.44)
F^a	1.09 (6.94)			1.86 (6.94)			2.40 (5.78)

^aThe figures between parenthesis are the tabulated t and F values, respectively are at P = 0.05 [81]
^bEach result was the average of three separate determinations

Back to article page

ISSN: 2661-801X

Contact us

Submission enquiries: bmcchemistry@biomedcentral.com
General enquiries: ORSupport@springernature.com