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Table 2 Effect of compounds 8 g and 12e on the expression of Bax, Bcl-xL and Bcl2 genes

From: Targeting apoptosis; design, synthesis and biological evaluation of new benzoxazole and thiazole based derivatives

Sample

RT-PCR results fold change

Compound number

Cells

IC50 (ug/ml)

Bax

Bcl-xL

Bcl-2

8g

HCT-116

89

3.864

0.251

0.31

12e

HCT-116

112

2.834

0.314

0.415

Control

–

–

1

1

1

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BMC Chemistry

ISSN: 2661-801X

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