Compound | Mw | LogP | Log Sa | Log Caco-2b | %HIAc |
---|
4k | 356 | 1.96 | − 3.394 | 0.97 | 94.3 |
4l | 394.16 | 3.0 | − 3.823 | 0.259 | 90.671 |
Kojic acid | 142.1 | − 0.162 | − 1.69 | 0.64 | 88 |
- aPredicted aqueous solubility in mol L−1 (− 6.5 to 0.5) (QPlogS > − 5.7)
- bPredicted Caco-2 cell permeability of a given compound is given as the log Papp in 10−6 cm/s (high Caco-2 permeability has LogCaco-2 > 0.9)
- cPercent of human intestinal absorption, (< 30% is poor and > 30% is high)